News & Analysis on the Clinical Development and Manufacture of Large Molecule Drugs
Upstream processes can be intensified using high cell density cryopreservation, perfused seed train or production processes with steady-state perfusion, or dynamic perfusion. In this white paper, we explore perfusion processes and how they are becoming a viable solution.
In this technical note, we investigate the interactions between the following: The spike glycoprotein binding with ACE2, Spike glycoprotein and anti-spike antibodies (mAb/ pAb), The spike glycoprotein binding with mAb/pAb to inhibit the interaction with ACE2
Development of a high-producing cell line supported by a robust upstream process are critical early steps in the production of monoclonal antibodies (mAbs). Optimization of this upstream workflow is essential to deliver a sufficiently high titer to...
For more product information visit Take the Right Path Upstream with MilliporeSigma.