The number of clinical trials featuring RNA-based drug products has increased dramatically since 2020. Infectious disease and cancer are the main targets (83%) for these clinical trials and, while some use antisense oligos (ASOs), small interfering RNA (siRNA) and other RNA modalities, the vast majority of these use mRNA. Given this interest, it is no surprise that the mRNA cancer vaccines and therapeutics market was estimated to be worth about $47 billion in 2021 and is projected to grow to $109 billion by 2028.
