News & Analysis on the Clinical Development and Manufacture of Large Molecule Drugs
Effective drug discovery and development relies on the availability of predictive preclinical model systems. Technologies based on human induced pluripotent stem cells (hiPSC) hold great promise to overcome this challenge.
In this application note researchers from Ncardia® show how they developed a bioprocess for the large-scale manufacturing of cardiomyocytes derived from a variety of healthy and diseased hiPSC lines for implementation into their DiscoverHIT platform.
A must-read for all bioprocess scientists: This bundle of four ebooks created by Eppendorf guides you through the world of upstream bioprocessing.
Experimentation at small scale is crucial for the cost-efficient development of bioprocesses, which then can be transferred to larger volumes. We have proven the feasibility of ATF-based perfusion using the DASGIP Parallel Bioreactor System.
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