The key to developing an elegant, robust and manufacturing-ready process starts during cell line and process development. Early identification of the expression system and isolation of the best clonal cell line is key to “getting it right the first time” early in the development process. The optimization of steps to isolate the best recombinant cell lines created using our select host cell line and vector has been in the mind of our scientists in the development of our Apollo Expression Platform. This includes the introduction of platform screening procedures which are more relevant to platform production processes where titers of up to 3 g/L have been observed.