In the U.S., a second high potency suite is being added to the company’s 128,000 sq ft Orthodox Street facility in Philadelphia.
The suite, to be completed by Q4 2024, will provide encapsulation, high-shear granulation, blending and other manufacturing processes.
It will complement the site’s existing potent suite, which provides roller compaction, milling, bin blending and tablet compression.
“We have seen demand for high potency handling and packaging continue to increase, with around half of solid dose drugs in development being highly potent,” said Tom Sellig, CEO of Adare Pharma Solutions.
“This proactive investment across our global network of sites will ensure we continue to provide customers with the oral dose capabilities and capacity they will need both now and in the future.”
The Orthodox Street site will also add a bottle packaging line providing turnkey support for highly potent clinical supplies and commercial products.
The high potency bottle packaging line will be operational in Q4 of 2024, the company said.
In addition, Adare’s 179,000 sq ft Vandalia facility in Ohio will upgrade several R&D-to-clinical stage production suites to provide high potency handling.
Capabilities will include dry roller compaction, microencapsulation, and fluid bed processing, with work already underway and scheduled for completion by Q4 of 2024.
In Europe, the CDMO’s 220,000 sq ft Pessano facility in Milan, Italy will add high potency upgrades to its analytical and formulation laboratories, including fluid bed processing, bin blending, compression, encapsulation and pan-coating capabilities.
The Pessano site also recently announced plans to add packaging capabilities and more warehousing capacity, as well as high-shear granulation mixing that can utilize either aqueous or organic-based solutions.
These expansions, as well as the high potency upgrades, will be operational by the end of 2024.
